Bootstrapping Course: Welcome

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Featured Videos

The Startup Velocity Question: What Hinders Acceleration in VC Funded Companies?

I have been running 1Mby1M since 2010. I find myself saying to entrepreneurs ad nauseam that VCs want to invest in startups that can go from zero to $100 million in revenue in 5 to 7 years.

Startups that do not have what it takes to achieve velocity should not be venture funded.

Experienced VCs, over time, have developed heuristics to gauge what constitutes a high growth venture investment thesis. 

June 12 – 689th 1Mby1M Mentoring Roundtable for Entrepreneurs

Entrepreneurs are invited to the 689th FREE online 1Mby1M Mentoring Roundtable on Thursday, June 12, 2025, at 8 a.m. PDT / 11 a.m. EDT / 5 p.m. CEST / 8:30 p.m. India IST.

If you are a serious entrepreneur, register to Pitch and sell your business idea. You’ll receive straightforward feedback, advice on next steps, and answers to any of your questions. Others can register to Attend to watch, learn, and interact through the online chat.

You can learn more here and REGISTER TO PITCH OR ATTEND HERE. Register and you will receive the recording by email, even if you are unable to attend. Please share with any entrepreneurs in your circle who may be Interested.

Featured Videos

688th 1Mby1M Roundtable Recording

In case you missed it, you can listen to the recording of this roundtable here:

Roundtable Recap: June 5 – Why You Should Avoid 3-Month Accelerators

During this week’s roundtable, I spoke about the changing landscape in the startup ecosystem. Among other things, it is becoming increasingly evident that the 3-month accelerator is broken except in very specific cases.

You can listen to the recording of this roundtable here:

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Video FAQs

Analysis of Perplexity AI’s Carbon Acquisition

According to a recent report, the AI market is estimated to grow at 37% CAGR from $279 billion in 2024 to $1.8 trillion by 2030. Perplexity AI continues to make its presence felt in the market with the launch of new offerings.

Building a High Growth Vertical AI Company in Healthcare: Ganesh Padmanabhan, CEO of Autonomize AI (Part 4)

Sramana Mitra: Healthcare is big, but it’s cumbersome. It’s one of the biggest exit barrier systems, right? You’ve all these legacy systems that refuse to exit, that refuse to budge, and entrepreneurs have a really hard time getting their toehold – not even foothold – toehold into those homes.

Where did you find the entry point of something that you could sell?

688th 1Mby1M Roundtable for Entrepreneurs Starting in 10 Minutes

Today’s 688th FREE online 1Mby1M Roundtable for Entrepreneurs is starting in 10 minutes, on Thursday, June 5, at 8 a.m. PDT / 11 a.m. EDT / 5 p.m. CEST / 8:30 p.m. India IST. CLICK HERE to join. PASSWORD: startup  All are welcome!

Building a High Growth Vertical AI Company in Healthcare: Ganesh Padmanabhan, CEO of Autonomize AI (Part 3)

Sramana Mitra: How long did you stay there?

Ganesh Padmanabhan: About two and a half years. During that time, we went from about $3 million to about $30 million ARR. It was very fast growth. It was early days of AI and we learned a lot.

Building a High Growth Vertical AI Company in Healthcare: Ganesh Padmanabhan, CEO of Autonomize AI (Part 2)

Sramana Mitra: Okay. So, now I have a picture of your timeline to double click down on. So, tell me about the startup that you did – where you got acqui-hired. How long was that journey?